Wednesday, 15 March 2017

The Hardy- Weinberg Equilibrum

For a 2 allele situation the Hardy- Weinberg Equilibrium is the best to use......

REMEMBER THIS...

p2 + 2pq + q2 = 1
 
P and Q are the frequencies of the alleles A and a
 
 
p2 + 2pq + q2 = 1
(AA)  +  (Aa)  +  (aa) = 1
 
 
At the Equilibrium, allele frequency does not change over time
 
 
EXAMPLE;
 
A particular species of fish is rarely seen, however we can find eggs and sperm in the water
(these are haploid = 1)  
 
  • The dominant allele 'R' codes for red scale colour
  • The recessive allele 'r' codes for white scale colour
80% where 0.8 had  Dominate 'R'
20% where 0.2 had recessive 'r'
 
RR (p2)- 0.8 x 0.8 = 0.64
Rr (pq)- 0.8 x 0.2 = 0.16
rR (pq)- 0.2 x 0.8 = 0.16
rr (q2) - 0.2 x 0.2 = 0.04
 
add all the numbers together the total should = 1




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